Anybody else's eyes get bothered by sprite-based games?

[bluberry]

I can sit there all day playing Chaos Legion and Devil May Cry (and even some polygonal sidescrollers like Contra: Shattered Soldier), but for the last year or so lots of older games tend to wreak havoc on my eyes. I just tried to play Shienryu and I had to squint after more than a few minutes, and I haven't fared much better with games like ThunderForce IV and El Viento. It's sort of like hard/uncomfortable to focus on the screen. I'm just kind of curious, does this happen to anybody else?

(Un)Interestingly enough, it also sometimes happens at movies.