The other day, I happened to be playing Monopoly on the Virtual NES site. I hadn't played the game in years and completely forgot that there's actual speech during gameplay in two instances (at the end of auctions, the auctioneer yells "SOLD!" and when a person leaves jail, a cop says "Don't be coming back now"). It got me wondering, what other NES games have speech in them?
Besides Monopoly, the only other game off the top of my head is Wisdom Tree's "Joshua," which was (of course) unlicensed.
EDIT: I also want to say Super Jeopardy! has brief speech from the host (most definitely NOT Alex Trebek).