*i.e. power outage, someone tripping over a cord or console, game freezing up randomly, someone intentionally disconnecting power while you're playing

I've been pretty lucky but the only things that come to mind are maybe an NES game freezing up if I left it paused for too long. Some of those games were so hard ans it would suck if you had to start all the way over from the beginning if you wanted to turn it off and come back to it.

I've randomly lost save files now and then. 1st gen Pokemon games come to mind. Lost a Crystalis save file recently. I think I had forgotten to hold down Reset while pressing the power button.

I haven't had any power outages affect gaming. Usually when it has happened, I'd be on my phone so I wasn't affected.