I remember back in the NES heyday, there was some morning talk show that was discussing kids with "Nintendonitis", which is where you get sore thumbs, or your wrists start hurting after playing with a Nintendo pad for so long. Kids would go to school and their wrists would hurt when they started writing, etc. And of course, the show went on to prove that video games are evil and will corrupt your child for life.
I had Nintendoitis, my thumbs and wrists would hurt like hell after one single game of Super Mario Bros. (No thanks to that masochistic NES pad.) My mom started to notice but fortunately she didn't really act on it. I had heard plenty of stories about parents restricting their kids from video games because of Nintendonitis, though.
But I soon found the cure- the NES Advantage. Playing with an arcade stick made all the difference in the world; rather than having my hands folded around a game pad with my thumbs doing all the work,(And growing sore against the hard plastic buttons) I can lay my hands down, with two comfortably positioned fingers sharing the workload, and my pinky ready to hit the pause button if need be. The direction was controlled by my thumb, index finger and forearm all working together, putting no strain on one perticular part of my hand. My hands felt fine after hours of play and I haven't used a game pad since. (Though I had to when the SNES came out, and I hated it.)
The only problem for me arised when I played an arcade game like Double Dragon or Crime fighters, tapping the attack button really puts the hurts on my wrist after a while. One day I was determined to finish Crime Fighters, and after stage 4 I had to pause the game, (MAME) hold an icepack to my tortured wrist for about 15 minutes, then pick the game back up. I had to do that three times before I finished the game. But now I have autofire available for all applications where I need it, (Shooters and beat'em ups) so that's taken care of.
What about you, huh?