I don't have enough experience to start this off with a full preliminary list, so I will be adding games that are mentioned at least twice.
What needs to be added? Did someone already suggest your favorites? Second their suggestion. Did someone suggest a game you think is terrible? Let us know. Discuss!
Agent USA
Alley Cat
Alternate Reality
Archon
Boulder Dash
Bounty Bob Strikes Back
Donkey Kong
Dreadnaught Factor
Dropzone
International Karate
Jumpman
Jumpman Jr.
Karateka
Lode Runner
M.U.L.E.
Mercenary
Miner 2049er
Montezuma's Revenge
Mr. Robot and His Robot Factory
Pinball Construction Set
Racing Destruction Set
Seven Cities of Gold
Shamus
Star Fleet I
Star Raiders
Ultima
Zeppelin
I'm hoping this will turn into a full top 50 list.