For me has to be those game phase guys from final fantasy 6 (they are head and they kinda look like buddha) annoying about em is they dont allow to you escape battles can get really annoying cause if your only backtracking for something , the look and abilities of this character are annoyin.
and 2nd for me is those laser eye enemies from zelda oot , I just want to kick his ass but he really slows down the action for me in that game.