Quote Originally Posted by Ed Oscuro View Post
Aside from multiplayer - there shouldn't be any advantage to using one build of MAME or another when it comes to compatibility with the MAME drivers. Some builds, like MAME Plus! actually offer console and other extended drivers, but I don't even know where to find them in the GUI let alone play games with them.
I remember that in order to play the home versions of the NeoGeo games, you had to right click on a game, go to Properties (Options?) and choose the region / bios that way. Home/Arcade, US/Japan/Asia/Europe, and so on.