MESS is a good point to be made. I use MESS to take screen shots of Tomy Tutor games for one of my columns at Retrogaming Times Monthly, as it's one of the few emulation platforms that run them. I've BARELY configured MESS and have encountered problems getting things to run but I've been able to work them out eventually. If I was going to be using it all the time then I'd spend more time on setting it up, but I'll probably only run the Tomy Tutor fork for like two hours total ever, so it's not worth it to me.
In that way it's just like the MAME discussion here, where you have to spend some time getting things configured if you're going to use the program on a regular basis.
stalepie - you aren't that dude that's been on a personal crusade to attempt to bring down MAME on a bunch of other forums, are you?