I have to confess....
I've never played Super Mario Bros 3. I've also never played the first 2 Doom's. Same with Grand Theft Auto 3.
I think I just got sick of the SMB series after playing 1 and 2 to death. Didn't play much of Super Mario World when I got my SNES, either. I love Doom 3, never know why I never played the first 2. Probably because I didn't get my first PC until '98. My parents forbid games on theirs. Didn't think the console ports would be any good. GTA3.... Haven't a clue. I've played all the other ones. And I even have the Xbox GTA double pack! But I bought it for Vice City. Okay, you can laugh it up now
So is there a major game you have just never played? I'm sure I've got a ton more, but I just can't think of any at the moment. I'm sure all of us have at least 1...