The 16-bit era was definitely the best era in gaming in my opinion. Genesis and SNES were both really good systems, and there was a lot of variety between the two. Best console war and system era ever.

The weakest for me was by far the 32-bit era. At least in America, there were some really sucky systems released over here at the time. You had the CD-i, Jaguar, the 3D0, the Pippin, the Virtual Boy, the Saturn (in terms of games here, NOT in terms of imports and hardware specs), and the Playstation.

All 6 of those systems were poor to mediocre showings:

Jaguar - All around horrible
3D0 - Overpriced, had no games
Virtual Boy - The red/back screen killed it
CD-i - All around horrible
Pippin - All around horrible
Saturn - Wasted potential, no new Sonic game, disappointing US library.
Playstation - Ruined the market for years to come. Never really had any killer-apps IMO.