At the most generalized level I'd say I'm on the BUY camp.
Although you only asked for the IN GENERAL case, I think it's the special circumstances that are more interesting and telling of what defines you. Also since you were debating about MUSHA, I think merely clinging to very highly general "rules of thumb" isn't the right way to go (imho of course). Sure it can make life simpler, but nuances are important.... at least more important to me.
if it's only a couple hundred bucks or a few thousand, no I'll keep it. If it's in the tens of thousands or more then yes I'll think about it. It's relative that way I suppose. What's a few grand going to do for me? Not much unless I lose my job, rainy day savings, general savings, retirement, other physical assets, various properties, etc.
Another thing is what makes the game so valuable? If it's just a "slight" variation in the packaging (subjective call) such as the Sonic UPC thing, then I'm more inclined to sell also. However if it's truly a "unique game" (one example: only available in this region in this format), then I'm more inclined to keep it.
Bottom line I don't think there are hard and fast, black and white borders to this issue.... or more importantly, there shouldn't be. Although I stated in the beginning that I'm on the BUY camp, I think that's just a result of the experiences/opportunities I've encountered so far. In theory, everyone has a fuzzy boundary on the topic when you look at it more closely with a microscope or they're not being entirely honest with themselves imho. At the "high level" you may be a BUY ONLY guy vs. SELL but given certain situations and parameters that can change. In addition there's a plethora of other issues I'm leaving out here such as collector vs. gamer... for example I'm a collector for retro but I view myself as more of a gamer for modern stuff. Therefore I'd be more apt to chuck a "valuable" "modern" object than a "retro" one. That all lies with the level of attachment to certain things according to whatever classification/grouping. The list of "special conditions" could go on and on...
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